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BMCBI
2011
14 years 10 months ago
nocoRNAc: Characterization of non-coding RNAs in prokaryotes
Background: The interest in non-coding RNAs (ncRNAs) constantly rose during the past few years because of the wide spectrum of biological processes in which they are involved. Thi...
Alexander Herbig, Kay Nieselt
125
Voted
BMCBI
2011
14 years 10 months ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...
190
Voted
BMCBI
2011
14 years 10 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
156
Voted
BMCBI
2011
14 years 10 months ago
ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
Mi-Youn K. Brusniak, Sung-Tat Kwok, Mark Christian...
BMCBI
2011
14 years 10 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
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