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BMCBI
2006
148views more  BMCBI 2006»
14 years 12 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
BMCBI
2006
113views more  BMCBI 2006»
14 years 12 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2007
115views more  BMCBI 2007»
14 years 11 months ago
Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
Background: Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct e...
Tobias Kind, Oliver Fiehn
BMCBI
2007
78views more  BMCBI 2007»
14 years 11 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
CGF
2007
156views more  CGF 2007»
14 years 11 months ago
Automatic Light Source Placement for Maximum Visual Information Recovery
The automatic selection of good viewing parameters is a very complex problem. In most cases, the notion of good strongly depends on the concrete application. Moreover, when an int...
Pere-Pau Vázquez