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BMCBI
2007
160views more  BMCBI 2007»
15 years 4 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
KDD
1998
ACM
140views Data Mining» more  KDD 1998»
15 years 8 months ago
Blurring the Distinction between Command and Data in Scientific KDD
We have been working on two different KDD systems for scientific data. One system involves comparative genomics, where the database contains more than 60,000 plant gene and protei...
John V. Carlis, Elizabeth Shoop, Scott Krieger
BMCBI
2010
115views more  BMCBI 2010»
15 years 4 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
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BMCBI
2010
100views more  BMCBI 2010»
15 years 4 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2007
132views more  BMCBI 2007»
15 years 4 months ago
Analysis of probe level patterns in Affymetrix microarray data
Background: Microarrays have been used extensively to analyze the expression profiles for thousands of genes in parallel. Most of the widely used methods for analyzing Affymetrix ...
Alexander C. Cambon, Abdelnaby Khalyfa, Nigel G. F...