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» Visual Network Analysis of Dynamic Metabolic Pathways
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BIOCOMP
2006
14 years 11 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BIOADIT
2004
Springer
15 years 3 months ago
Analysis of Responses of Complex Bionetworks to Changes in Environmental Conditions
Abstract. The responses of flexible bionetworks to extreme environmental changes were studied in several microorganisms. Gene and metabolic networks markedly changed with osmotic ...
Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahis...
BMCBI
2007
93views more  BMCBI 2007»
14 years 9 months ago
The topology of metabolic isotope labeling networks
Background: Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways. Isotope labeling ...
Michael Weitzel, Wolfgang Wiechert, Katharina N&ou...
BMCBI
2006
205views more  BMCBI 2006»
14 years 9 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
166views more  BMCBI 2006»
14 years 9 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto