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» Visual Network Analysis of Dynamic Metabolic Pathways
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BMCBI
2006
145views more  BMCBI 2006»
14 years 9 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BIOCOMP
2009
14 years 10 months ago
Evolution of Domain Compositions in the Metabolic Networks of Human and Escherichia Coli
It is widely recognized that complexity of metabolic networks arises from duplication, recruitment and recombination of enzyme protein domains. However, variations of the domain ev...
Chen-Hsiang Yeang, Nils Baas
CMSB
2003
Springer
15 years 2 months ago
An Overview of Data Models for the Analysis of Biochemical Pathways
Biochemical pathways such as metabolic, regulatory or signal tranduction pathways can be viewed as interconnected processes forming an intricate network of functional and physical...
Yves Deville, David Gilbert, Jacques van Helden, S...
BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2008
153views more  BMCBI 2008»
14 years 9 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani