Intracellular signaling pathways as well as the interactions and coordination that exist among them are complex and difficult to visualize and understand. Computer-based models of...
Biochemical pathways or networks are generic representations used to model many different types of complex functional and physical interactions in biological systems. Models based ...
Patrick Doherty, Steve Kertes, Martin Magnusson, A...
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...