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BMCBI
2006
171views more  BMCBI 2006»
15 years 2 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
105
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ICCAD
1997
IEEE
121views Hardware» more  ICCAD 1997»
15 years 6 months ago
Adaptive methods for netlist partitioning
An algorithm that remains in use at the core of many partitioning systems is the Kernighan-Lin algorithm and a variant the Fidducia-Matheysses (FM) algorithm. To understand the FM...
Wray L. Buntine, Lixin Su, A. Richard Newton, Andr...
IDA
2005
Springer
15 years 8 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2006
165views more  BMCBI 2006»
15 years 2 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2004
161views more  BMCBI 2004»
15 years 2 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi