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BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
15 years 4 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...
BMCBI
2008
126views more  BMCBI 2008»
15 years 4 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
ADAC
2010
124views more  ADAC 2010»
15 years 1 months ago
Methods for merging Gaussian mixture components
The problem of merging Gaussian mixture components is discussed in situations where a Gaussian mixture is fitted but the mixture components are not separated enough from each othe...
Christian Hennig
BMCBI
2007
120views more  BMCBI 2007»
15 years 4 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2010
132views more  BMCBI 2010»
15 years 4 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter