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BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
15 years 2 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...
BMCBI
2008
126views more  BMCBI 2008»
15 years 2 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
ADAC
2010
124views more  ADAC 2010»
14 years 11 months ago
Methods for merging Gaussian mixture components
The problem of merging Gaussian mixture components is discussed in situations where a Gaussian mixture is fitted but the mixture components are not separated enough from each othe...
Christian Hennig
BMCBI
2007
120views more  BMCBI 2007»
15 years 2 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2010
132views more  BMCBI 2010»
15 years 2 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter