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ISPA
2005
Springer
15 years 7 months ago
COMPACT: A Comparative Package for Clustering Assessment
Abstract. There exist numerous algorithms that cluster data-points from largescale genomic experiments such as sequencing, gene-expression and proteomics. Such algorithms may emplo...
Roy Varshavsky, Michal Linial, David Horn
BMCBI
2008
145views more  BMCBI 2008»
15 years 2 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
118
Voted
BMCBI
2006
95views more  BMCBI 2006»
15 years 2 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
BIOINFORMATICS
2011
14 years 5 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
101
Voted
BMCBI
2006
131views more  BMCBI 2006»
15 years 2 months ago
inGeno - an integrated genome and ortholog viewer for improved genome to genome comparisons
Background: Systematic genome comparisons are an important tool to reveal gene functions, pathogenic features, metabolic pathways and genome evolution in the era of post-genomics....
Chunguang Liang, Thomas Dandekar