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BMCBI
2004
144views more  BMCBI 2004»
14 years 11 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
CSR
2006
Springer
15 years 3 months ago
Fast Motif Search in Protein Sequence Databases
Regular expression pattern matching is widely used in computational biology. Searching through a database of sequences for a motif (a simple regular expression), or its variations...
Elena Zheleva, Abdullah N. Arslan
BMCBI
2006
107views more  BMCBI 2006»
14 years 12 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
14 years 12 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BMCBI
2006
147views more  BMCBI 2006»
14 years 12 months ago
QPath: a method for querying pathways in a protein-protein interaction network
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...