Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
Paolo Ferragina, Raffaele Giancarlo, Valentina Gre...
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
We study suitable indexing techniques to support efficient exact match search in large biological sequence databases. We propose a suffix tree (ST) representation, called STA-DF, ...
Mihail Halachev, Nematollaah Shiri, Anand Thamildu...