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RECOMB
2008
Springer
16 years 5 days ago
Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer
Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
Cuong Than, Guohua Jin, Luay Nakhleh
RECOMB
2006
Springer
16 years 5 days ago
Domain Architecture in Homolog Identification
Homology identification is the first step for many genomic studies. Current methods, based on sequence comparison, can result in a substantial number of mis-assignments due to the ...
Nan Song, R. D. Sedgewick, Dannie Durand
BMCBI
2002
126views more  BMCBI 2002»
14 years 11 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
JCB
2007
136views more  JCB 2007»
14 years 11 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...
BMCBI
2002
76views more  BMCBI 2002»
14 years 11 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman