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» Visualization of Gene Combinations
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BMCBI
2007
153views more  BMCBI 2007»
15 years 6 months ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...
BMCBI
2008
124views more  BMCBI 2008»
15 years 6 months ago
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
Romesh Stanislaus, Mark Carey, Helena F. Deus, Kev...
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
BMCBI
2004
200views more  BMCBI 2004»
15 years 6 months ago
ABC: software for interactive browsing of genomic multiple sequence alignment data
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...
ICML
2008
IEEE
16 years 7 months ago
Expectation-maximization for sparse and non-negative PCA
We study the problem of finding the dominant eigenvector of the sample covariance matrix, under additional constraints on the vector: a cardinality constraint limits the number of...
Christian D. Sigg, Joachim M. Buhmann