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117
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BMCBI
2007
119views more  BMCBI 2007»
15 years 25 days ago
Conceptual-level workflow modeling of scientific experiments using NMR as a case study
Background: Scientific workflows improve the process of scientific experiments by making computations explicit, underscoring data flow, and emphasizing the participation of humans...
Kacy K. Verdi, Heidi J. C. Ellis, Michael R. Gryk
81
Voted
BMCBI
2007
79views more  BMCBI 2007»
15 years 25 days ago
Orthology prediction at scalable resolution by phylogenetic tree analysis
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
René T. J. M. van der Heijden, Berend Snel,...
105
Voted
BMCBI
2007
138views more  BMCBI 2007»
15 years 25 days ago
A full Bayesian hierarchical mixture model for the variance of gene differential expression
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...
Samuel O. M. Manda, Rebecca E. Walls, Mark S. Gilt...
70
Voted
BMCBI
2008
98views more  BMCBI 2008»
15 years 25 days ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
111
Voted
BMCBI
2008
80views more  BMCBI 2008»
15 years 25 days ago
Towards an automatic classification of protein structural domains based on structural similarity
Background: Formal classification of a large collection of protein structures aids the understanding of evolutionary relationships among them. Classifications involving manual ste...
Vichetra Sam, Chin-Hsien Tai, Jean Garnier, Jean-F...
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