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BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2011
14 years 4 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
RECOMB
2005
Springer
15 years 10 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
BIB
2010
129views more  BIB 2010»
14 years 9 months ago
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
Peter D. Karp, Suzanne M. Paley, Markus Krummenack...
NAR
2011
191views Computer Vision» more  NAR 2011»
14 years 16 days ago
ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabol...
Atanas Kamburov, Konstantin Pentchev, Hanna Galick...