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BMCBI
2008
174views more  BMCBI 2008»
14 years 12 months ago
Evolutionary approaches for the reverse-engineering of gene regulatory networks: A study on a biologically realistic dataset
Background: Inferring gene regulatory networks from data requires the development of algorithms devoted to structure extraction. When only static data are available, gene interact...
Cédric Auliac, Vincent Frouin, Xavier Gidro...
BMCBI
2008
186views more  BMCBI 2008»
14 years 12 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2008
90views more  BMCBI 2008»
14 years 12 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
BMCBI
2010
139views more  BMCBI 2010»
14 years 12 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
BMCBI
2007
81views more  BMCBI 2007»
14 years 12 months ago
PADB : Published Association Database
Background: Although molecular pathway information and the International HapMap Project data can help biomedical researchers to investigate the aetiology of complex diseases more ...
Hwanseok Rhee, Jin-Sung Lee