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BMCBI
2006
152views more  BMCBI 2006»
15 years 3 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
GEOINFORMATICA
2008
123views more  GEOINFORMATICA 2008»
15 years 3 months ago
Efficient Implementation Techniques for Topological Predicates on Complex Spatial Objects
Topological relationships like overlap, inside, meet, and disjoint uniquely characterize the relative position between objects in space. For a long time, they have been a focus of...
Reasey Praing, Markus Schneider
BMCBI
2006
190views more  BMCBI 2006»
15 years 3 months ago
VANTED: A system for advanced data analysis and visualization in the context of biological networks
Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisti...
Björn H. Junker, Christian Klukas, Falk Schre...
BMCBI
2006
85views more  BMCBI 2006»
15 years 3 months ago
Quality control for terms and definitions in ontologies and taxonomies
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
Jacob Köhler, Katherine Munn, Alexander R&uum...
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BMCBI
2006
169views more  BMCBI 2006»
15 years 3 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...