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101
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BMCBI
2010
15 years 1 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
116
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BMCBI
2010
15 years 1 months ago
2010
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
113
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BMCBI
2010
15 years 1 months ago
2010
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
117
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BMCBI
2008
15 years 1 months ago
2008
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...
134
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BMCBI
2008
15 years 1 months ago
2008
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...