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BMCBI
2008
148views more  BMCBI 2008»
14 years 9 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...
BMCBI
2010
128views more  BMCBI 2010»
14 years 9 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
BMCBI
2006
184views more  BMCBI 2006»
14 years 9 months ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...
BMCBI
2006
130views more  BMCBI 2006»
14 years 9 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2007
121views more  BMCBI 2007»
14 years 9 months ago
e-Science and biological pathway semantics
Background: The development of e-Science presents a major set of opportunities and challenges for the future progress of biological and life scientific research. Major new tools a...
Joanne S. Luciano, Robert D. Stevens