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BMCBI
2006
88views more  BMCBI 2006»
14 years 11 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
BMCBI
2006
84views more  BMCBI 2006»
14 years 11 months ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
80
Voted
BMCBI
2006
131views more  BMCBI 2006»
14 years 11 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
93
Voted
BMCBI
2006
117views more  BMCBI 2006»
14 years 11 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
ISF
2008
114views more  ISF 2008»
14 years 11 months ago
An OVAL-based active vulnerability assessment system for enterprise computer networks
Abstract Many security problems are caused by vulnerabilities hidden in enterprise computer networks. It is very important for system administrators to have knowledge about the sec...
Xiuzhen Chen, Qinghua Zheng, Xiaohong Guan