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BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2007
134views more  BMCBI 2007»
14 years 9 months ago
A framework for significance analysis of gene expression data using dimension reduction methods
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...
BMCBI
2010
214views more  BMCBI 2010»
14 years 9 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
85
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NIPS
2003
14 years 11 months ago
ICA-based Clustering of Genes from Microarray Expression Data
We propose an unsupervised methodology using independent component analysis (ICA) to cluster genes from DNA microarray data. Based on an ICA mixture model of genomic expression pa...
Su-In Lee, Serafim Batzoglou
BMCBI
2010
118views more  BMCBI 2010»
14 years 9 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...