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BMCBI
2010
161views more  BMCBI 2010»
14 years 11 months ago
GATExplorer: Genomic and Transcriptomic Explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs
Background: Genome-wide expression studies have developed exponentially in recent years as a result of extensive use of microarray technology. However, expression signals are typi...
Alberto Risueño, Celia Fontanillo, Marcel E...
BMCBI
2011
14 years 6 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
BMCBI
2004
146views more  BMCBI 2004»
14 years 11 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
BMCBI
2008
98views more  BMCBI 2008»
14 years 11 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2006
86views more  BMCBI 2006»
14 years 11 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...