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BMCBI
2007
156views more  BMCBI 2007»
14 years 9 months ago
Large-scale clustering of CAGE tag expression data
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
BMCBI
2007
107views more  BMCBI 2007»
14 years 9 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
BMCBI
2008
126views more  BMCBI 2008»
14 years 9 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BMCBI
2006
119views more  BMCBI 2006»
14 years 9 months ago
Evaluation of microarray data normalization procedures using spike-in experiments
Background: Recently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-ca...
Patrik Rydén, Henrik Andersson, Mattias Lan...
BMCBI
2008
94views more  BMCBI 2008»
14 years 9 months ago
A comprehensive re-analysis of the Golden Spike data: Towards a benchmark for differential expression methods
Background: The Golden Spike data set has been used to validate a number of methods for summarizing Affymetrix data sets, sometimes with seemingly contradictory results. Much less...
Richard D. Pearson