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BMCBI
2006
115views more  BMCBI 2006»
14 years 9 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2008
133views more  BMCBI 2008»
14 years 9 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
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BMCBI
2010
94views more  BMCBI 2010»
14 years 9 months ago
Comparison study of microarray meta-analysis methods
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
Anna Campain, Yee Hwa Yang
BMCBI
2011
14 years 4 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
BMCBI
2008
98views more  BMCBI 2008»
14 years 9 months ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...