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BMCBI
2010
15 years 28 days ago
2010
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
93
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BMCBI
2008
15 years 28 days ago
2008
Background: As an alternative to the frequently used "reference design" for two-channel microarrays, other designs have been proposed. These designs have been shown to b...
100
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BMCBI
2008
15 years 28 days ago
2008
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
99
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BMCBI
2010
15 years 28 days ago
2010
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
89
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BMCBI
2008
15 years 28 days ago
2008
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...