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93
Voted
BMCBI
2008
78views more  BMCBI 2008»
15 years 28 days ago
Evaluation of time profile reconstruction from complex two-color microarray designs
Background: As an alternative to the frequently used "reference design" for two-channel microarrays, other designs have been proposed. These designs have been shown to b...
Ana C. Fierro, Raphael Thuret, Kristof Engelen, Gi...
100
Voted
BMCBI
2008
146views more  BMCBI 2008»
15 years 28 days ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
99
Voted
BMCBI
2010
128views more  BMCBI 2010»
15 years 28 days ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
89
Voted
BMCBI
2008
136views more  BMCBI 2008»
15 years 28 days ago
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
Harald Binder, Martin Schumacher
101
Voted
BMCBI
2008
88views more  BMCBI 2008»
15 years 28 days ago
Microarray-based gene set analysis: a comparison of current methods
Background: The analysis of gene sets has become a popular topic in recent times, with researchers attempting to improve the interpretability and reproducibility of their microarr...
Sarah Song, Michael A. Black
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