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» What is a Biological Function
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122
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BMCBI
2010
131views more  BMCBI 2010»
14 years 10 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom
150
Voted
BMCBI
2011
14 years 7 months ago
ASPDock: protein-protein docking algorithm using atomic solvation parameters model
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
146
Voted
BMCBI
2011
14 years 7 months ago
PheMaDB: A solution for storage, retrieval, and analysis of high throughput phenotype data
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
Wenling E. Chang, Keri Sarver, Brandon W. Higgs, T...
103
Voted
STOC
2007
ACM
134views Algorithms» more  STOC 2007»
16 years 28 days ago
Hardness of routing with congestion in directed graphs
Given as input a directed graph on N vertices and a set of source-destination pairs, we study the problem of routing the maximum possible number of source-destination pairs on pat...
Julia Chuzhoy, Venkatesan Guruswami, Sanjeev Khann...
COCO
2003
Springer
118views Algorithms» more  COCO 2003»
15 years 5 months ago
Lower bounds for predecessor searching in the cell probe model
We consider a fundamental problem in data structures, static predecessor searching: Given a subset S of size n from the universe [m], store S so that queries of the form “What i...
Pranab Sen