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BMCBI
2010
138views more  BMCBI 2010»
15 years 27 days ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
100
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BMCBI
2008
146views more  BMCBI 2008»
15 years 27 days ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
DEBU
2008
125views more  DEBU 2008»
15 years 25 days ago
Querying XML in Timber
In this paper, we describe the TIMBER XML database system implemented at University of Michigan. TIMBER was one of the first native XML database systems, designed from the ground ...
Yuqing Wu, Stelios Paparizos, H. V. Jagadish
AIM
2006
15 years 25 days ago
Comparative Analysis of Frameworks for Knowledge-Intensive Intelligent Agents
maintain awareness of its environment for a long period of time. Additionally, knowledge-intensive agents must be engineered such that their knowledge can be easily updated as envi...
Randolph M. Jones, Robert E. Wray III
123
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BMCBI
2006
116views more  BMCBI 2006»
15 years 25 days ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...