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99
Voted
BMCBI
2010
15 years 26 days ago
2010
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
92
Voted
BMCBI
2010
15 years 26 days ago
2010
Background: Some of the recent investigations in systems biology have revealed the existence of a complex regulatory network between genes, microRNAs (miRNAs) and transcription fa...
128
Voted
BMCBI
2010
15 years 26 days ago
2010
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
105
Voted
BMCBI
2010
15 years 26 days ago
2010
Background: With the biomedical literature continually expanding, searching PubMed for information about specific genes becomes increasingly difficult. Not only can thousands of r...
113
Voted
BMCBI
2007
15 years 26 days ago
2007
Background: Natural antisense transcripts (NATs) are endogenous RNA molecules that exhibit partial or complete complementarity to other RNAs, and that may contribute to the regula...