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BMCBI
2005
90views more  BMCBI 2005»
14 years 11 months ago
An algorithm for the determination and quantification of components of nucleic acid mixtures based on single sequencing reaction
Background: Determination and quantification of nucleic acid components in a mixture is usually accomplished by microarray approaches, where the mixtures are hybridized against sp...
Alexander E. Pozhitkov, Kathryn Stemshorn, Diethar...
BMCBI
2005
77views more  BMCBI 2005»
14 years 11 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
BMCBI
2005
117views more  BMCBI 2005»
14 years 11 months ago
HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Researc
Background: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. Th...
Marcella Attimonelli, Matteo Accetturo, Monica San...
BMCBI
2004
122views more  BMCBI 2004»
14 years 11 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich
BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz