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BMCBI
2008
123views more  BMCBI 2008»
14 years 11 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2006
107views more  BMCBI 2006»
14 years 11 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
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BMCBI
2006
127views more  BMCBI 2006»
14 years 11 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2007
207views more  BMCBI 2007»
14 years 11 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...
NAR
2006
120views more  NAR 2006»
14 years 11 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...