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BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
97views more  BMCBI 2006»
14 years 9 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
155views more  BMCBI 2006»
14 years 9 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
BMCBI
2006
96views more  BMCBI 2006»
14 years 9 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
Genomes as geography: using GIS technology to build interactive genome feature maps
Background: Many commonly used genome browsers display sequence annotations and related attributes as horizontal data tracks that can be toggled on and off according to user prefe...
Mary E. Dolan, Constance C. Holden, M. Kate Beard,...