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BMCBI
2005
60views more  BMCBI 2005»
15 years 10 days ago
PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
Background: Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the...
Florent Angly, Beltran Rodriguez-Brito, David Bang...
BMCBI
2004
94views more  BMCBI 2004»
15 years 9 days ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields
116
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BMCBI
2004
165views more  BMCBI 2004»
15 years 9 days ago
Analysis of oligonucleotide array experiments with repeated measures using mixed models
Background: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients...
Hao Li, Constance L. Wood, Thomas V. Getchell, Mar...
104
Voted
SAC
2004
ACM
15 years 5 months ago
Guiding motif discovery by iterative pattern refinement
In this paper, we demonstrate that the performance of a motif discovery algorithm can be significantly improved by embedding it into a novel framework that effectively guides the ...
Zhiping Wang, Mehmet M. Dalkilic, Sun Kim
KDD
2004
ACM
145views Data Mining» more  KDD 2004»
16 years 26 days ago
Mining coherent gene clusters from gene-sample-time microarray data
Extensive studies have shown that mining microarray data sets is important in bioinformatics research and biomedical applications. In this paper, we explore a novel type of genesa...
Daxin Jiang, Jian Pei, Murali Ramanathan, Chun Tan...