We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
Genome sequencing opened a new era in genetics allowing the study of genomes at the nucleotide level. However, the chosen method of sequencing produced large numbers of nucleotide...
Human Papilloma Virus (HPV) is a sexually transmitted virus, which can lead to cervical cancer. HPV DNA is found in cervical cancers with types 16, 18, 31 and 45 accounting for mo...
We describe a new method to predict the tertiary structure of new-fold proteins. Our two-phase approach combines the knowledge-based fragmentpacking with the minimization of a phy...
Jinhui Ding, Elizabeth Eskow, Nelson L. Max, Silvi...