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CSB
2005
IEEE
116views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Oscillatory dynamics in the mitogen-activated protein kinase cascade
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
K.-H. Chiam, Vipul Bhargava, Gunaretnam Rajagopal
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
15 years 3 months ago
TreeRefiner: A Tool for Refining a Multiple Alignment on a Phylogenetic Tree
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
Aswath Manohar, Serafim Batzoglou
CSB
2005
IEEE
132views Bioinformatics» more  CSB 2005»
15 years 15 hour ago
A Fast Shotgun Assembly Heuristic
Genome sequencing opened a new era in genetics allowing the study of genomes at the nucleotide level. However, the chosen method of sequencing produced large numbers of nucleotide...
Christopher Wilks, Sami Khuri
BIBE
2005
IEEE
15 years 3 months ago
Predicting Human Papilloma Virus Prevalence and Vaccine Policy Effectiveness in Demographic Strata
Human Papilloma Virus (HPV) is a sexually transmitted virus, which can lead to cervical cancer. HPV DNA is found in cervical cancers with types 16, 18, 31 and 45 accounting for mo...
Courtney Corley, Armin R. Mikler
CSB
2005
IEEE
117views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Protein Structure Prediction Using Physical-Based Global Optimization and Knowledge-Guided Fragment Packing
We describe a new method to predict the tertiary structure of new-fold proteins. Our two-phase approach combines the knowledge-based fragmentpacking with the minimization of a phy...
Jinhui Ding, Elizabeth Eskow, Nelson L. Max, Silvi...