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CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Inverse Design of Large Molecules using Linear Diophantine Equations
We have previously developed a method [1] for the inverse design of small ligands. This method can be used to design novel compounds with optimized properties (such as drugs) and ...
Shawn Martin, W. Michael Brown, Jean-Loup Faulon, ...
CSB
2005
IEEE
167views Bioinformatics» more  CSB 2005»
15 years 3 months ago
SinicView: An Interactive Visualization Tool for Comparison of Multiple Sequence Alignment Results
In the initial stage of sequence analysis, a biologist is first faced with the questions about how to choose the best tool to align sequences of interest and how to analyze and v...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...
CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali
CSB
2005
IEEE
152views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Consensus Genetic Maps: A Graph Theoretic Approach
A genetic map is an ordering of genetic markers constructed from genetic linkage data for use in linkage studies and experimental design. While traditional methods have focused on...
Benjamin G. Jackson, Srinivas Aluru, Patrick S. Sc...