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PREMI
2005
Springer
15 years 3 months ago
Computational Molecular Biology of Genome Expression and Regulation
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...
Michael Q. Zhang
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 3 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
WEA
2005
Springer
176views Algorithms» more  WEA 2005»
15 years 3 months ago
High-Performance Algorithm Engineering for Large-Scale Graph Problems and Computational Biology
Abstract. Many large-scale optimization problems rely on graph theoretic solutions; yet high-performance computing has traditionally focused on regular applications with high degre...
David A. Bader
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 3 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...