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BMCBI
2006
180views more  BMCBI 2006»
14 years 10 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
109views more  BMCBI 2006»
14 years 10 months ago
iHOPerator: user-scripting a personalized bioinformatics Web, starting with the iHOP website
Background: User-scripts are programs stored in Web browsers that can manipulate the content of websites prior to display in the browser. They provide a novel mechanism by which u...
Benjamin M. Good, Edward A. Kawas, Byron Yu-Lin Ku...
BIOINFORMATICS
2006
87views more  BIOINFORMATICS 2006»
14 years 10 months ago
COPASI - a COmplex PAthway SImulator
Simulation and modeling is becoming one of the standard approaches to understand complex biochemical processes. Therefore, there is a big need for software tools that allow access...
Stefan Hoops, Sven Sahle, Ralph Gauges, Christine ...
BIOINFORMATICS
2006
130views more  BIOINFORMATICS 2006»
14 years 10 months ago
Memory efficient folding algorithms for circular RNA secondary structures
A small class of RNA molecules, in particular the tiny genomes of viroids, are circular. Yet most structure prediction algorithms handle only linear RNAs. The most straightforward ...
Ivo L. Hofacker, Peter F. Stadler
BIOINFORMATICS
2006
96views more  BIOINFORMATICS 2006»
14 years 10 months ago
Joint estimation of calibration and expression for high-density oligonucleotide arrays
Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...