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FGCS
2007
78views more  FGCS 2007»
14 years 10 months ago
Experiences with GeneRecon on MiG
We report on our experiences so far with running a bioinformatics simulation study on a newly developed Grid architecture. We briefly describe the bioinformatics application – ...
Thomas Mailund, Christian N. S. Pedersen, Jonas Ba...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 10 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
14 years 10 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BIOINFORMATICS
2006
120views more  BIOINFORMATICS 2006»
14 years 10 months ago
Comparison of Affymetrix GeneChip expression measures
Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
Rafael A. Irizarry, Zhijin Wu, Harris A. Jaffee
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
14 years 10 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...