Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
Roel G. W. Verhaak, Mathijs A. Sanders, Maarten A....
Background: With the advances in DNA sequencer-based technologies, it has become possible to automate several steps of the genotyping process leading to increased throughput. To e...
B. Jayashree, Praveen T. Reddy, Y. Leeladevi, Jona...
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...