Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Co-clustering is the simultaneous partitioning of the rows and columns of a matrix such that the blocks induced by the row/column partitions are good clusters. Motivated by severa...
Aris Anagnostopoulos, Anirban Dasgupta, Ravi Kumar
RNA structure prediction, or folding, is a computeintensive task that lies at the core of several search applications in bioinformatics. We begin to address the need for high-thro...
Arpith C. Jacob, Jeremy Buhler, Roger D. Chamberla...
— This paper presents an approach to the multiple sequence alignment (MSA) problem by applying genetic algorithms with a reserve selection mechanism. MSA is one of the most funda...
Yang Chen, Jinglu Hu, Kotaro Hirasawa, Songnian Yu