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BMCBI
2008
158views more  BMCBI 2008»
14 years 12 months ago
VarDetect: a nucleotide sequence variation exploratory tool
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Chumpol Ngamphiw, Supasak Kulawonganunchai, Anunch...
BMCBI
2008
106views more  BMCBI 2008»
14 years 12 months ago
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Mikel Egaña Aranguren, Erick Antezana, Mart...
PODS
2008
ACM
153views Database» more  PODS 2008»
15 years 12 months ago
Approximation algorithms for co-clustering
Co-clustering is the simultaneous partitioning of the rows and columns of a matrix such that the blocks induced by the row/column partitions are good clusters. Motivated by severa...
Aris Anagnostopoulos, Anirban Dasgupta, Ravi Kumar
ASAP
2008
IEEE
186views Hardware» more  ASAP 2008»
15 years 6 months ago
Accelerating Nussinov RNA secondary structure prediction with systolic arrays on FPGAs
RNA structure prediction, or folding, is a computeintensive task that lies at the core of several search applications in bioinformatics. We begin to address the need for high-thro...
Arpith C. Jacob, Jeremy Buhler, Roger D. Chamberla...
ICNSC
2008
IEEE
15 years 6 months ago
Multiple Sequence Alignment Based on Genetic Algorithms with Reserve Selection
— This paper presents an approach to the multiple sequence alignment (MSA) problem by applying genetic algorithms with a reserve selection mechanism. MSA is one of the most funda...
Yang Chen, Jinglu Hu, Kotaro Hirasawa, Songnian Yu