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BIOSYSTEMS
2007
109views more  BIOSYSTEMS 2007»
14 years 10 months ago
Complex adaptation and system structure
The structural organization of biological systems is one of nature’s most fascinating aspects, but its origin and functional role is not yet fully understood. For instance, basi...
Marc Toussaint, Werner von Seelen
BIOSYSTEMS
2007
115views more  BIOSYSTEMS 2007»
14 years 10 months ago
Evolving fuzzy rules to model gene expression
This paper develops an algorithm that extracts explanatory rules from microarray data, which we treat as time series, using genetic programming (GP) and fuzzy logic. Reverse polis...
Ricardo Linden, Amit Bhaya
BIOSYSTEMS
2007
123views more  BIOSYSTEMS 2007»
14 years 10 months ago
Real time computation: Zooming in on population codes
Information processing in nervous systems intricately combines computation at the neuronal and network levels. Many computations may be envisioned as sequences of signal processin...
Olivier Rochel, Netta Cohen
BIOSYSTEMS
2007
104views more  BIOSYSTEMS 2007»
14 years 10 months ago
New structural variation in evolutionary searches of RNA neutral networks
RNA secondary structure is an important computational model to understand how genetic variation maps into phenotypic (structural) variation. Evolutionary innovation in RNA structu...
Sumedha, Olivier C. Martin, Andreas Wagner
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
14 years 10 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright