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BMCBI
2004
129views more  BMCBI 2004»
14 years 10 months ago
Integrating partonomic hierarchies in anatomy ontologies
Background Anatomy ontologies play an increasingly important role in developing integrated bioinformatics applications. One of the primary relationships between anatomical tissues...
Albert Burger, Duncan Davidson, Yiya Yang, Richard...
BMCBI
2004
113views more  BMCBI 2004»
14 years 10 months ago
Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide array
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
BMCBI
2004
120views more  BMCBI 2004»
14 years 10 months ago
Clustering under the line graph transformation: application to reaction network
Background: Many real networks can be understood as two complementary networks with two kind of nodes. This is the case of metabolic networks where the first network has chemical ...
Jose C. Nacher, Nobuhisa Ueda, Takuji Yamada, Mino...
BMCBI
2004
94views more  BMCBI 2004»
14 years 10 months ago
The MB2 gene family of Plasmodium species has a unique combination of S1 and GTP-binding domains
Background: Identification and characterization of novel Plasmodium gene families is necessary for developing new anti-malarial therapeutics. The products of the Plasmodium falcip...
Lisa C. Romero, Thanh Vinh Nguyen, Benoit Deville,...
BMCBI
2004
154views more  BMCBI 2004»
14 years 10 months ago
Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells
Background: cDNA microarrays are a powerful means to screen for biologically relevant gene expression changes, but are often limited by their ability to detect small changes accur...
Bin Yao, Sanjay N. Rakhade, Qunfang Li, Sharlin Ah...