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BMCBI
2004
14 years 10 months ago
2004
Background: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In t...
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BMCBI
2004
14 years 10 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
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BMCBI
2004
14 years 10 months ago
2004
Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
BMCBI
2004
14 years 10 months ago
2004
Background: Mass spectrometry based proteomics result in huge amounts of data that has to be processed in real time in order to efficiently feed identification algorithms and to e...
BMCBI
2004
14 years 10 months ago
2004
Background: Because loops connect regular secondary structures, analysis of the former depends directly on the definition of the latter. The numerous assignment methods, however, ...