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BMCBI
2004
127views more  BMCBI 2004»
14 years 10 months ago
Optimized LOWESS normalization parameter selection for DNA microarray data
Background: Microarray data normalization is an important step for obtaining data that are reliable and usable for subsequent analysis. One of the most commonly utilized normaliza...
John A. Berger, Sampsa Hautaniemi, Anna-Kaarina J&...
BMCBI
2004
94views more  BMCBI 2004»
14 years 10 months ago
The tissue microarray data exchange specification: implementation by the Cooperative Prostate Cancer Tissue Resource
Background: Tissue Microarrays (TMAs) have emerged as a powerful tool for examining the distribution of marker molecules in hundreds of different tissues displayed on a single sli...
Jules J. Berman, Milton Datta, Andre Kajdacsy-Ball...
BMCBI
2004
112views more  BMCBI 2004»
14 years 10 months ago
MuTrack: a genome analysis system for large-scale mutagenesis in the mouse
Background: Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanni...
Erich J. Baker, Leslie Galloway, Barbara Jackson, ...
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BMCBI
2004
111views more  BMCBI 2004»
14 years 10 months ago
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Background: Transcriptional regulation of cellular functions is carried out through a complex network of interactions among transcription factors and the promoter regions of genes...
Radu Dobrin, Qasim K. Beg, Albert-Lászl&oac...
BMCBI
2004
120views more  BMCBI 2004»
14 years 10 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...