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BMCBI
2004
14 years 10 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
104
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BMCBI
2004
14 years 10 months ago
2004
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
BMCBI
2004
14 years 10 months ago
2004
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
BMCBI
2004
14 years 10 months ago
2004
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
121
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BMCBI
2004
14 years 10 months ago
2004
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...