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BMCBI
2004
14 years 10 months ago
2004
Background: Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channe...
BMCBI
2004
14 years 10 months ago
2004
Background: There are two different theories about the development of the genetic code. Woese suggested that it was developed in connection with the amino acid repertoire, while C...
BMCBI
2004
14 years 10 months ago
2004
Background: SUPFAM database is a compilation of superfamily relationships between protein domain families of either known or unknown 3-D structure. In SUPFAM, sequence families fr...
BMCBI
2004
14 years 10 months ago
2004
Background: The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate speci...
BMCBI
2004
14 years 10 months ago
2004
The hit criterion is a key component of heuristic local alignment algorithms. It specifies a class of patterns assumed to witness a potential similarity, and this choice is decisi...