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BMCBI
2004
121views more  BMCBI 2004»
14 years 10 months ago
Asynchronous adaptive time step in quantitative cellular automata modeling
Background: The behaviors of cells in metazoans are context dependent, thus large-scale multicellular modeling is often necessary, for which cellular automata are natural candidat...
Hao Zhu, Peter Y. H. Pang, Yan Sun, Pawan Dhar
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BMCBI
2004
125views more  BMCBI 2004»
14 years 10 months ago
A fast algorithm for determining the best combination of local alignments to a query sequence
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
Gavin C. Conant, Andreas Wagner
BMCBI
2004
181views more  BMCBI 2004»
14 years 10 months ago
Iterative class discovery and feature selection using Minimal Spanning Trees
Background: Clustering is one of the most commonly used methods for discovering hidden structure in microarray gene expression data. Most current methods for clustering samples ar...
Sudhir Varma, Richard Simon
BMCBI
2004
108views more  BMCBI 2004»
14 years 10 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
BMCBI
2004
116views more  BMCBI 2004»
14 years 10 months ago
Array-A-Lizer: A serial DNA microarray quality analyzer
Background: The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consiste...
Andreas Petri, Jan Fleckner, Mads Wichmann Matthie...