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BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions
Background: A Nanopore Detector provides a means to transduce single molecule events into observable channel current changes. Nanopore-based detection can report directly, or indi...
Stephen Winters-Hilt
BMCBI
2006
130views more  BMCBI 2006»
14 years 10 months ago
Identifying biological concepts from a protein-related corpus with a probabilistic topic model
Background: Biomedical literature, e.g., MEDLINE, contains a wealth of knowledge regarding functions of proteins. Major recurring biological concepts within such text corpora repr...
Bin Zheng, David C. McLean Jr, Xinghua Lu
BMCBI
2006
68views more  BMCBI 2006»
14 years 10 months ago
Detecting overlapping coding sequences in virus genomes
Background: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding...
Andrew E. Firth, Chris M. Brown
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
On the persistence of supplementary resources in biomedical publications
Background: Providing for long-term and consistent public access to scientific data is a growing concern in biomedical research. One aspect of this problem can be demonstrated by ...
Nicholas R. Anderson, Peter Tarczy-Hornoch, Roger ...
BMCBI
2006
84views more  BMCBI 2006»
14 years 10 months ago
Phase analysis of circadian-related genes in two tissues
Background: Recent circadian clock studies using gene expression microarray in two different tissues of mouse have revealed not all circadian-related genes are synchronized in pha...
Delong Liu, Shyamal D. Peddada, Leping Li, Clarice...