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BMCBI
2006
64views more  BMCBI 2006»
14 years 10 months ago
In silico modelling of hormone response elements
Background: An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types...
Maria Stepanova, Feng Lin, Valerie C.-L. Lin
BMCBI
2006
100views more  BMCBI 2006»
14 years 10 months ago
Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas
Background: Expression microarrays represent a powerful technique for the simultaneous investigation of thousands of genes. The evidence that genes are not randomly distributed in...
Federico E. Turkheimer, Federico Roncaroli, Benoit...
BMCBI
2006
85views more  BMCBI 2006»
14 years 10 months ago
On the statistical assessment of classifiers using DNA microarray data
Background: In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new d...
Nicola Ancona, Rosalia Maglietta, Ada Piepoli, Ann...
BMCBI
2008
77views more  BMCBI 2008»
14 years 10 months ago
A simple and robust method for connecting small-molecule drugs using gene-expression signatures
Background: Interaction of a drug or chemical with a biological system can result in a geneexpression profile or signature characteristic of the event. Using a suitably robust alg...
Shu-Dong Zhang, Timothy W. Gant
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BMCBI
2006
104views more  BMCBI 2006»
14 years 10 months ago
GNU polyxmass: a software framework for mass spectrometric simulations of linear (bio-)polymeric analytes
Background: Nowadays, a variety of (bio-)polymers can be analyzed by mass spectrometry. The detailed interpretation of the spectra requires a huge number of "hypothesis cycle...
Filippo Rusconi