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88
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BMCBI
2006
124views more  BMCBI 2006»
14 years 10 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...
Petras J. Kundrotas, Emil Alexov
110
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BMCBI
2006
187views more  BMCBI 2006»
14 years 10 months ago
Detecting outliers when fitting data with nonlinear regression - a new method based on robust nonlinear regression and the false
Background: Nonlinear regression, like linear regression, assumes that the scatter of data around the ideal curve follows a Gaussian or normal distribution. This assumption leads ...
Harvey J. Motulsky, Ronald E. Brown
BMCBI
2006
164views more  BMCBI 2006»
14 years 10 months ago
BIOZON: a system for unification, management and analysis of heterogeneous biological data
Integration of heterogeneous data types is a challenging problem, especially in biology, where the number of databases and data types increase rapidly. Amongst the problems that o...
Aaron Birkland, Golan Yona